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Women having chemotherapy for early breast cancer were randomly assigned to wear a machine-cooled cap or not. About half of those who used the cap kept most of their hair; none of the others did.
SCALP randomised 182 women at seven US sites to Paxman scalp cooling (119) or no cooling (63). At the planned interim analysis 142 were evaluable: 36 per cent had anthracycline-based and 64 per cent taxane-based chemotherapy. Hair preservation (grade 0 or 1 alopecia) was seen in 48 of 95 women who used cooling (50.5 per cent) and 0 of 47 controls; because the result crossed the superiority boundary, the data and safety monitoring board recommended stopping the trial on 26 September 2016. There were no significant differences in quality-of-life scales by cycle four. The result supported the FDA clearance of the Paxman Scalp Cooler in April 2017 (K163484).
Numbers are from the trial as recorded here; see the source links in the table below. This is orientation, not medical advice: ask your team how closely the trial population matches you.
Shares Comfort devices at the chemotherapy chair: scalp cooling, cold caps, limb cryocompression and infusion chairs, Scalp cooling (cold caps: DigniCap, Paxman) and the tag machines-wave3.
Shares Comfort devices at the chemotherapy chair: scalp cooling, cold caps, limb cryocompression and infusion chairs, Scalp cooling (cold caps: DigniCap, Paxman), Breast cancer (all types) and the tag machines-wave3.
Shares Comfort devices at the chemotherapy chair: scalp cooling, cold caps, limb cryocompression and infusion chairs, Scalp cooling (cold caps: DigniCap, Paxman) and the tag machines-wave3.
Shares Paxman and the tag machines-wave3.
Shares Comfort devices at the chemotherapy chair: scalp cooling, cold caps, limb cryocompression and infusion chairs, Scalp cooling (cold caps: DigniCap, Paxman), Breast cancer (all types) and the tag machines-wave3.
Shares Paxman and the tag machines-wave3.
Shares Comfort devices at the chemotherapy chair: scalp cooling, cold caps, limb cryocompression and infusion chairs and the tag machines-wave3.
Shares Paxman, Comfort devices at the chemotherapy chair: scalp cooling, cold caps, limb cryocompression and infusion chairs, Scalp cooling (cold caps: DigniCap, Paxman), Breast cancer (all types) and the tag machines-wave3.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/