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Home
Cancers
Erdheim-Chester disease
Data

Cancers·Erdheim-Chester disease

DataErdheim-Chester disease

Back to the Erdheim-Chester disease hub →33 connected records

Every connected record, the notes, the JSON, Markdown and RDF twins, and where the record came from and when it was checked.

Overview Types and stages Symptoms and diagnosis Treatment Trials and papers Biology and targets Countries and centres Decisions and support Pipeline and open problems Data

Data

Related pages

33

Direct links plus the targets, companies, and technologies of this cancer's products.

Similar pages

Cancer
Advanced systemic mastocytosis (aggressive SM, SM with an associated haematological neoplasm, mast cell leukaemia)
Shares WHO classification of haematolymphoid tumours, fifth edition: myeloid and histiocytic neoplasms, Cladribine, Interferon alfa-2a/2b, Driver mutation and the tags subtype-page, haematologic.
Cancer
Indolent and smouldering systemic mastocytosis
Shares WHO classification of haematolymphoid tumours, fifth edition: myeloid and histiocytic neoplasms, Cladribine, Interferon alfa-2a/2b, Driver mutation and the tags subtype-page, haematologic.
Cancer
Nodular lymphocyte-predominant Hodgkin lymphoma (nodular lymphocyte-predominant B-cell lymphoma)
Shares Active surveillance, FDG PET and the tags subtype-page, haematologic.
Cancer
Advanced-stage classical Hodgkin lymphoma (stage III to IV)
Shares FDG PET and the tags subtype-page, haematologic.
Cancer
Early-stage classical Hodgkin lymphoma (stage I to II)
Shares FDG PET and the tags subtype-page, haematologic.
Cancer
Relapsed and refractory classical Hodgkin lymphoma
Shares FDG PET and the tags subtype-page, haematologic.
Cancer
Single-system Langerhans cell histiocytosis (bone, skin or one other organ)
Shares Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages, Cladribine, Rosai-Dorfman-Destombes disease, BRAF V600E mutation and the tag subtype-page.
Cancer
Langerhans cell histiocytosis (LCH)
Shares Histiocytosis Association, ARAF, Cladribine, Multisystem Langerhans cell histiocytosis (with or without risk-organ involvement) and the tag haematologic.

technologies

Active surveillance Comprehensive genomic profiling Cytokines & engineered cytokines Cytotoxic chemotherapy FDG PET Liquid biopsy (ctDNA)MRI Small-molecule kinase inhibitors

targets

ARAF BRAF PIK3CA / PI3K-alpha

drugs

ApprovedPurine nucleoside analogue

Cladribine · Leustatin / Litak

ApprovedSmall-molecule kinase inhibitor (MEK1/2)

Cobimetinib · Cotellic

ApprovedSmall-molecule kinase inhibitors (BRAF + MEK)

Dabrafenib + trametinib · Tafinlar + Mekinist

HistoricRecombinant type I interferon (cytokine)

Interferon alfa-2a/2b · Roferon-A / Intron A / Sylatron

ApprovedAntifolate (DHFR inhibitor)

Methotrexate · Trexall / Otrexup / Xatmep

ApprovedSmall-molecule kinase inhibitor (BRAF V600)

Vemurafenib · Zelboraf

companies

Biomed Valley Discoveries Johnson & Johnson Merck & Co. (MSD)Novartis Roche / Genentech

institutions

Histiocytosis Association

pathways

RAS / RAF / MEK / ERK (MAPK)

terms

BRAF V600E mutation Circulating tumour DNA (ctDNA)Driver mutation Retroperitoneum

key papers

Efficacy of MEK inhibition in patients with histiocytic neoplasms Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis and treatment in the molecular era Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages VE-BASKET: vemurafenib for BRAF V600-mutant Erdheim-Chester disease and Langerhans cell histiocytosis WHO classification of haematolymphoid tumours, fifth edition: myeloid and histiocytic neoplasms

Machine-readable versions

The same record for scripts and assistants; checked 2026-09-18. Data CC BY-NC 4.0, attribute “Data from OnCo (onco.cc)”.

JSON with neighbours Markdown context RDF Turtle Sections with routes and counts API root

Wikipedia

Erdheim–Chester disease

subtype-page haematologic

Make correction

Machine-readable versions of Erdheim-Chester disease

JSON record with neighbours
Markdown context for language models
RDF Turtle for this record (its triples, relations and owl:sameAs; the IRI of this record is https://onco.cc/cancers/erdheim-chester-disease/)
Section plan: the ten sections of this record with routes, anchors and counts
All cancers as JSON
RDF N-Triples for the whole corpus
Search index: id, kind, name, TL;DR and route for every record
OpenAPI 3.1 description
API root and meta.json
llms.txt

MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id erdheim-chester-disease.

WebMCP tools registered on this page: onco_search, onco_get_entity.