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Everything in development, the open problems and what is being done about them, the roadmaps, and what changed on this record.
What is in development for HER2-positive breast cancer with brain metastases, drawn from the whole corpus: 9 items. Drugs are grouped by the most advanced trial phase they have reached anywhere; approved treatments sit under standard of care. Technologies are the methods being tested for this cancer, trials are the studies recorded here, and ideas are proposals not yet in a trial.
No randomised trial has compared systemic therapy first with radiosurgery first for asymptomatic lesions.
Leptomeningeal disease still has no proven treatment.
Background: HER2-positive brain metastases. Also on OnCo: Atlas of advanced disease · How cancer spreads: the metastasis stages.
Radionecrosis after radiosurgery may be commoner with antibody-drug conjugates.
Screening MRI might find lesions earlier but no trial shows it helps.
Nothing recorded yet.
Nothing recorded yet.
Also on OnCo: Symptoms and red flags · Early detection roadmap.
Dated changes read from the records linked to this cancer: approvals, regulatory steps, reported trials, guideline versions and milestones. Newest first; no date is inferred.
On EdgeAll 17 changes by month →When this page itself was last checked or edited.
PFS 24.
A milestone in how this cancer is treated.
CNS ORR 71.
A milestone in how this cancer is treated.
PFS 9.