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The decisions you may face, the aids that walk through them, the warnings on record, the first sixty days and the questions to ask.
One section per setting: the options named, what each is for, the trials behind them, the recorded trade-offs and the questions to ask.
Fainting, near-fainting, or an irregular or racing heartbeat; several kinase inhibitors prolong the QT interval and the labels require ECG and electrolyte monitoring.
Bleeding that will not stop, black or bloody stools, or unexplained bruising when platelets are expected to be low.
Sudden severe abdominal pain, a hard or very tender abdomen, or abdominal pain with vomiting and fever. Boxed warning for gastrointestinal perforation on bevacizumab.
Persistent headache with extreme tiredness, nausea, dizziness on standing or low blood pressure. Vomiting, severe weakness or collapse is adrenal crisis.
Cumulative dose: risk rises steeply above 400-550 mg/m² (see the anthracycline calculator).
Take with a meal and a large glass of water.
See all on the product pages:AvapritinibDoxorubicinIfosfamideImatinibPazopanibPembrolizumabRipretinibTrabectedinVimseltinib·Printable cards in the navigator
Newly diagnosed? Read the first 60 days with Sarcomas, then print the one-page appointment sheet with room for the answers.
Print this page for your appointment (your browser's print command). These prompts are for discussion; your clinical team knows your case.