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CTAG1B (Cancer/testis antigen 1) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Multiple myeloma. This dossier gathers the 1 product (0 approved), 3 trials, 0 pathways and 0 resistance routes in the corpus that involve it, with external identifiers so it can be joined to UniProt, ChEMBL, Open Targets and the rest of biology.
UniProt has no function text for P78358; HGNC names it "cancer/testis antigen 1B". Location: Cytoplasm (UniProt). Locus Xq28 (HGNC).
| Modality | Phase 1 |
|---|---|
| Cell therapy 1 |
| Trial | Setting | Result | Products | ||
|---|---|---|---|---|---|
| 1 | Withdrawn | NY-ESO-1-expressing melanoma or sarcoma: cyclophosphamide, autologous CD4+ NY-ESO-1-specific T cells and ipilimumab | Withdrawn before enrolment (0 participants); registry reason: "Issues with tetramer staining". | ||
| 1 | Planned | A Phase 1 Study With Expansion of Patient-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-601) Administered To Patients With Locally Advanced Unresectable or Metastatic Pancreatic Cancer (PANACEA) | - | ||
| 1 | Recruiting | A Phase 1 Study of Patient-Derived Multi-Tumor-Associated Antigen-Specific T Cells (MT-601) Administered to Patients With Relapsed or Refractory Non-Hodgkin and Hodgkin Lymphoma (APOLLO) | - |
No recorded escape route names this target.
No pathway diagram carries this target as a node.
No companion diagnostic in the registry measures this target.
No model entry for this target yet; check the cancer entries on the models page.
No open questions recorded for this target yet. Suggest one.
Query for this target: (TITLE:"CTAG1B" OR ABSTRACT:"CTAG1B" OR TITLE:"cancer/testis antigen 1B" OR ABSTRACT:"cancer/testis antigen 1B" OR TITLE:"Cancer/testis antigen 1" OR ABSTRACT:"Cancer/testis antigen 1" OR TITLE:"NY-ESO-1" OR ABSTRACT:"NY-ESO-1" OR TITLE:"LAGE2B" OR ABSTRACT:"LAGE2B" OR TITLE:"LAGE2A" OR ABSTRACT:"LAGE2A") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CTAG1B, not a curated reading list.
The dossier as machine-readable JSON, at /api/v1/dossiers/ctag1b.json: identifiers from HGNC, Ensembl, UniProt and ChEMBL, products with status, trials, pathways, hotspots, open questions and assays. The full entity record is in the open API at /api/v1/entities/ctag1b.json. Licence CC BY-NC 4.0.