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AVL-101 is an experimental DNA-based therapeutic HPV vaccine from Beijing Xunsheng Biomedical Research, in phase 1 trials for cervical intraepithelial neoplasia grade 2/3 caused by HPV16/18.
AVL-101 is a DNA-based therapeutic HPV vaccine from Beijing Xunsheng Biomedical Research, with Beijing Anweituo Biomedicine Co., Ltd., subsidiary and trial sponsor as partner. A therapeutic HPV vaccine, not a preventive one: the company says it works by activating cytotoxic T cells that recognise and clear cells carrying HPV16/18, aiming for regression of the lesion and clearance of the virus. Its furthest stage is phase 1, for cervical intraepithelial neoplasia grade 2/3 (CIN2/3) caused by HPV16/18 (a cervical precancer). No clinical trial naming it is registered on ClinicalTrials.gov. Phase 1 site initiation meetings held 9 July 2026 (Tianjin Medical University General Hospital) and 30 July 2026 (Cancer Hospital, Chinese Academy of Medical Sciences), per company news. It has not been shown to work in people.
A therapeutic HPV vaccine, not a preventive one: the company says it works by activating cytotoxic T cells that recognise and clear cells carrying HPV16/18, aiming for regression of the lesion and clearance of the virus.
1.AVL-101 slips into a pocket on its target.
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Query for this drug: (TITLE:"AVL-101" OR ABSTRACT:"AVL-101") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about AVL-101, not a curated reading list.
Shares Beijing Xunsheng Biomedical Research and the tag pipeline.
Shares Beijing Xunsheng Biomedical Research and the tag pipeline.
Shares Beijing Xunsheng Biomedical Research and the tag pipeline.
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