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CBA-1205 is an experimental humanized afucosylated monoclonal antibody from Chiome Bioscience, in phase 1 trials for advanced solid tumours, hepatocellular carcinoma and melanoma and other cancers.
CBA-1205 is a humanized afucosylated monoclonal antibody (ADCC enhanced) from Chiome Bioscience. A humanized, afucosylated antibody against DLK-1, made with enhanced antibody-dependent cellular cytotoxicity (ADCC). Its furthest stage is phase 1, for advanced solid tumours, hepatocellular carcinoma, melanoma and paediatric cancer. ClinicalTrials.gov registers it in one study linked below. Phase 1 first-in-human study NCT06636435 recruiting per ClinicalTrials.gov (study start June 2020, first posted October 2024). Whether it works in people has not been established unless a trial below reports it.
A humanized, afucosylated antibody against DLK-1, made with enhanced antibody-dependent cellular cytotoxicity (ADCC).
1.CBA-1205 binds its target.
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Query for this drug: (TITLE:"CBA-1205" OR ABSTRACT:"CBA-1205") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CBA-1205, not a curated reading list.
Shares Chiome Bioscience, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Chiome Bioscience, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Chiome Bioscience, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Chiome Bioscience, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Chiome Bioscience and the tag pipeline.
Shares Hepatocellular carcinoma, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Neuroblastoma (paediatric), Hepatocellular carcinoma and the tag pipeline.
Shares Hepatocellular carcinoma, Melanoma, Metastatic cancer (cancer that has spread) and the tag pipeline.
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