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CYNK-001 is an experimental allogeneic, cryopreserved, off-the-shelf natural killer cell therapy derived from placental haematopoietic stem cells from Celularity, in phase 1 trials for acute myeloid leukaemia, glioblastoma and multiple myeloma; its current status is not stated.
CYNK-001 (placental-derived natural killer (CYNK) cells) is an allogeneic, cryopreserved, off-the-shelf natural killer (NK) cell therapy derived from placental haematopoietic stem cells from Celularity. Ready-made NK cells grown from placental stem cells; the company reports killing of myeloma, AML and glioblastoma cells in the laboratory. Its furthest stage is phase 1, for acute myeloid leukaemia, glioblastoma and multiple myeloma. ClinicalTrials.gov registers it in 4 studies linked below. Cancer trials ended: AML NCT04310592 terminated ('Business reasons'), glioblastoma NCT04489420 terminated ('Business decision.'), glioblastoma NCT05218408 withdrawn, myeloma NCT04309084 status unknown. The company now describes CYNK-001 as a potential treatment for age-related diseases, and its current pipeline page does not list it. Whether it works in people has not been established unless a trial below reports it.
Ready-made NK cells grown from placental stem cells; the company reports killing of myeloma, AML and glioblastoma cells in the laboratory.
1.CYNK-001 slips into a pocket on its target.
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Query for this drug: (TITLE:"CYNK-001" OR ABSTRACT:"CYNK-001" OR TITLE:"placental-derived natural killer CYNK cells" OR ABSTRACT:"placental-derived natural killer CYNK cells") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CYNK-001, not a curated reading list.
Shares Multiple myeloma, Acute myeloid leukaemia and the tag pipeline.
Shares Glioma & glioblastoma and the tag pipeline.
Shares Acute myeloid leukaemia and the tag pipeline.
Shares Acute myeloid leukaemia and the tag pipeline.
Shares Multiple myeloma and the tag pipeline.
Shares Glioma & glioblastoma and the tag pipeline.
Shares Glioma & glioblastoma and the tag pipeline.
Shares Glioma & glioblastoma and the tag pipeline.
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