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An MRI dye injected into a vein that is absorbed by healthy liver cells, so spots in the liver that are not normal liver tissue show up clearly. It is used to find and characterise liver tumours.
The FDA label (Bayer, NDA 022090, first approved 3 July 2008) says EOVIST "is indicated for use in magnetic resonance imaging (MRI) of the liver to detect and characterize lesions in adult and pediatric patients, including term neonates, with known or suspected focal liver disease". The WHO lists it as gadoxetic acid (ATC V08CA10). Like every gadolinium-based contrast agent in the United States, its label carries a boxed warning on the risks of intrathecal use and nephrogenic systemic fibrosis, a thickening of skin and organs seen in people with severe kidney disease.
A gadolinium chelate that shortens the relaxation time of nearby water protons, brightening tissue on MRI. Part of each dose is taken up by working liver cells, so lesions without normal liver cells stand out in the later images.
| Region | Year | Indication |
|---|---|---|
| US | 2008 | MRI of the liver to detect and characterise lesions in known or suspected focal liver disease · NDA 022090; Bayer |
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Query for this drug: (TITLE:"Gadoxetate disodium" OR ABSTRACT:"Gadoxetate disodium" OR TITLE:"liver-specific MRI contrast" OR ABSTRACT:"liver-specific MRI contrast" OR TITLE:"Eovist" OR ABSTRACT:"Eovist" OR TITLE:"gadoxetate" OR ABSTRACT:"gadoxetate" OR TITLE:"gadoxetic acid" OR ABSTRACT:"gadoxetic acid") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Gadoxetate disodium (liver-specific MRI contrast), not a curated reading list.
Shares Gadolinium-based and other MRI contrast agents, Bayer, MRI and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares Gadolinium-based and other MRI contrast agents, MRI and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares Gadolinium-based and other MRI contrast agents, Bayer, MRI and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares Gadolinium-based and other MRI contrast agents, MRI and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares Gadolinium-based and other MRI contrast agents, MRI and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares Gadolinium-based and other MRI contrast agents, MRI, Hepatocellular carcinoma and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares Gadolinium-based and other MRI contrast agents, MRI and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares Gadolinium-based and other MRI contrast agents, MRI and the tags contrast-agents-gaps-2026-11, diagnostic.
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