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Ilixadencel is an experimental allogeneic dendritic cell product injected into the tumour from Mendus, in phase 2 trials for metastatic renal cell carcinoma, hepatocellular carcinoma and gastrointestinal stromal tumour and other cancers; its current status is not stated.
Ilixadencel (Intuvax, COMBIG-DC) is an allogeneic dendritic cell product injected into the tumour from Mendus. Allogeneic dendritic cells injected directly into the tumour to start an immune response. Its furthest stage is phase 2, for metastatic renal cell carcinoma, hepatocellular carcinoma, gastrointestinal stromal tumour and head and neck, gastric and non-small cell lung cancer (with pembrolizumab). ClinicalTrials.gov registers it in 4 studies linked below. Phase 2 in newly diagnosed metastatic renal cell carcinoma (NCT02432846) completed; phase 1 with pembrolizumab (NCT03735290) terminated. No current development statement found on the company site. Whether it works in people has not been established unless a trial below reports it.
Allogeneic dendritic cells injected directly into the tumour to start an immune response.
1.Ilixadencel slips into a pocket on its target.
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Query for this drug: (TITLE:"Ilixadencel" OR ABSTRACT:"Ilixadencel" OR TITLE:"ilixadencel" OR ABSTRACT:"ilixadencel" OR TITLE:"Intuvax" OR ABSTRACT:"Intuvax" OR TITLE:"COMBIG-DC" OR ABSTRACT:"COMBIG-DC") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Ilixadencel, not a curated reading list.
Shares Renal cell carcinoma, Hepatocellular carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Mendus and the tag pipeline.
Shares Mendus and the tag pipeline.
Shares Mendus and the tag pipeline.
Shares Mendus and the tag pipeline.
Shares Renal cell carcinoma, Hepatocellular carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Renal cell carcinoma, Hepatocellular carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Renal cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
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