Israel's largest university and the academic parent of the Sheba, Sourasky and Rabin hospitals, so most Israeli oncology papers carry its name; its physics department is where the alpha-emitter radiotherapy behind Alpha Tau began.
Tel Aviv University's Gray Faculty of Medical and Health Sciences (formerly Sackler) is the academic affiliation of Sheba Medical Center, Tel Aviv Sourasky (Ichilov) and Rabin Medical Center, which is why a large share of Israeli clinical oncology publications carry a Tel Aviv University address alongside a hospital one. Its distinctive contribution of its own is Diffusing Alpha-emitters Radiation Therapy: Itzhak Kelson in physics and Yona Keisari in immunology devised seeds that release short-lived alpha-emitting daughter atoms which diffuse a few millimetres through a tumour, a route to alpha radiation that does not require a targeting molecule, and the work was licensed through the university's technology transfer company Ramot to Alpha Tau Medical. Zelig Eshhar, whose 1989 chimeric receptor is the ancestor of every CAR-T product, ran his later laboratory at Tel Aviv Sourasky within the same faculty.
Mapped which inherited cancer variants recur in which Israeli communities, and showed that outside the Ashkenazi founder panel there is no shortcut: you have to sequence.
A tumour immunologist who helped build Israel's melanoma cell therapy programme at Sheba and now runs the melanoma centre at Davidoff, publishing what checkpoint drugs do outside the clean conditions of a trial.
Built the melanoma and immunotherapy institute at Sheba that has been growing patients' own tumour-infiltrating lymphocytes and giving them back since 2006, more than a decade before any regulator approved the idea.
Runs the laboratory that actually grows the cells. Her papers are the reason anyone outside the United States believed a hospital could manufacture tumour-infiltrating lymphocytes reliably.
The immunologist who, in 1989, first gave a T cell an antibody's aim. Every CAR-T product on the market descends from that experiment.
Shares Gal Markel, Michal Besser, Jacob Schachter, Sheba Medical Center.
Shares Zelig Eshhar, CAR-T cell therapy.
Shares Eitan Friedman, Sheba Medical Center.
Shares Zelig Eshhar, Sheba Medical Center.
Shares Gal Markel, Michal Besser, Jacob Schachter, Sheba Medical Center.
Shares Sheba Medical Center, CAR-T cell therapy.