Francisca Vazquez
Francisca Vazquez leads DepMap, the public map of which genes each cancer cell line cannot live without.
Directs the Broad's Cancer Dependency Map, integrating genome-wide CRISPR and drug screens across more than 1,000 cell lines to reveal synthetic-lethal targets.
| Title | Journal | Year |
|---|---|---|
| Defining a cancer dependency map | Cell | 2017 |
Pages like this
not linked directly; found by shared links- PersonTodd R. Golub
Shares Broad Institute of MIT and Harvard, CRISPR functional genomics.
- PersonFeng Zhang
Shares Broad Institute of MIT and Harvard, CRISPR functional genomics.
- IdeaAttack the backup copy when a tumour has lost the original gene
Shares Synthetic lethality approaches, Broad Institute of MIT and Harvard, CRISPR functional genomics.
- IdeaAn open atlas of collateral sensitivity for every approved targeted drug
Shares Broad Institute of MIT and Harvard, CRISPR functional genomics.
- IdeaPRMT5/MAT2A synthetic lethality for MTAP-deleted mesothelioma
Shares Synthetic lethality approaches, CRISPR functional genomics.
- IdeaTurn chromosomal chaos into a weakness with KIF18A inhibitors
Shares Synthetic lethality approaches, CRISPR functional genomics.
- IdeaWRN inhibitors: a second synthetic-lethal win for mismatch-repair cancers
Shares Synthetic lethality approaches, CRISPR functional genomics.
- Key paperDefining a Cancer Dependency Map: which genes each cancer cell line cannot live without
Shares Synthetic lethality approaches, Broad Institute of MIT and Harvard, CRISPR functional genomics.