SPECT & bone scan
SPECT and the bone scan are an older type of nuclear scan, still used for bone metastases and to check where a radioactive drug went after treatment.
99mTc-MDP bone scan for skeletal metastases (being displaced by PSMA PET in prostate). SPECT/CT after 177Lu therapy enables post-treatment dosimetry, a key enabler of personalised radioligand dosing.
How it works
Gamma cameras detect single photons from 99mTc, 111In, 177Lu; rotating acquisition reconstructs 3D distribution.
- Cheap, widespread
- Dosimetry for radioligand therapy
- Lower resolution and sensitivity than PET
Latest papers
topQuery for this technology: (TITLE:"SPECT/CT" OR ABSTRACT:"SPECT/CT" OR TITLE:"bone scan" OR ABSTRACT:"bone scan" OR TITLE:"dosimetry SPECT" OR ABSTRACT:"dosimetry SPECT") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about SPECT & bone scan, not a curated reading list.