Loading
Cancer cell lines are tumour cells grown indefinitely in the laboratory; they are convenient for drug testing but only imperfectly stand in for a patient's tumour.
An immortalised cell line is a population of cells that has evaded normal senescence and can be grown for prolonged periods in vitro (Wikipedia). The Cancer Cell Line Encyclopedia and similar panels pair molecular profiles of about a thousand lines with drug screens, which is where most drug-response models are trained. Lines lack a microenvironment, immune system and drug pharmacokinetics, and drift in culture, so transfer from cell line to patient is a separate, harder problem.
Shares Drug response and drug sensitivity (IC50, AUC), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Drug response and drug sensitivity (IC50, AUC), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Domain shift and domain adaptation (cell line to patient), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Domain shift and domain adaptation (cell line to patient), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Domain shift and domain adaptation (cell line to patient), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Domain shift and domain adaptation (cell line to patient), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.