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PSA50 / PSA90 response

PSA50 is the share of patients whose PSA falls by at least half on treatment, and PSA90 the share whose PSA falls by 90%.

Standard early-efficacy read-out in mCRPC trials (VISION PSA50 46%; TheraP 66% vs 37%). Correlates with but does not replace rPFS/OS; PSA90 futility ended masofaniten's phase 2.

Endpoints: what this kind of term is about · animated schematic, not to scale
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Endpoints

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