termsTerm
PSA (prostate-specific antigen)
A blood protein made by the prostate; raised levels prompt further tests, and falling levels show treatment is working.
Screening test with proven mortality reduction (ERSPC ~20% at 16 years) but substantial overdiagnosis; now paired with MRI and risk-adapted intervals. In treated disease, PSA kinetics (doubling time, PSA50/PSA90 response, nadir) are the everyday response measure, though not a validated surrogate for survival in mCRPC.
Biomarkers: what this kind of term is about · animated schematic, not to scale
Category
Biomarkers