Vepdegestrant (ARV-471/PF-07850327) + Palbociclib vs Letrozole + Palbociclib in ER(+)/HER2(-) Advanced Breast Cancer
A phase 3 trial of Vepdegestrant and Palbociclib in advanced solid tumours, run by Pfizer, active and no longer recruiting.
Overview
Vepdegestrant (ARV-471/PF-07850327) + Palbociclib vs Letrozole + Palbociclib in ER(+)/HER2(-) Advanced Breast Cancer is a phase 3 interventional study registered as NCT05909397 by Pfizer, with 59 participants enrolled, started 2023-08-09 and due to reach its primary completion in 2026-12-30. Interventions recorded: Vepdegestrant (ARV-471/PF-07850327), Palbociclib and Letrozole.
Similar pages
not linked directly; found by shared links- TrialTACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)
Shares Vepdegestrant, Pfizer (incl. Seagen), Metastatic cancer (cancer that has spread) and the tag pipeline.
- TrialTACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B)
Shares Vepdegestrant, Pfizer (incl. Seagen), Metastatic cancer (cancer that has spread) and the tag pipeline.
- TrialA Study to Learn About Vepdegestrant When Given With PF-07220060 to People With Advanced or Metastatic Breast Cancer.
Shares Vepdegestrant, Pfizer (incl. Seagen), Metastatic cancer (cancer that has spread) and the tag pipeline.
- TrialTACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)
Shares Vepdegestrant, Pfizer (incl. Seagen), Metastatic cancer (cancer that has spread) and the tag pipeline.
- TrialSNV4818 in Participants With Advanced Solid Tumors
Shares Palbociclib, Metastatic cancer (cancer that has spread) and the tag pipeline.
- TrialA Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Shares Pfizer (incl. Seagen), Metastatic cancer (cancer that has spread) and the tag pipeline.
- TrialStudy for Participants Continuing From Pfizer-sponsored Palbociclib (a Study Medicine) Studies
Shares Palbociclib, Pfizer (incl. Seagen) and the tag pipeline.
- TrialA Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors
Shares Pfizer (incl. Seagen), Metastatic cancer (cancer that has spread) and the tag pipeline.