Emapalumab Prevention of CAR-T Cell Associated Toxicities
A phase 2 trial of Emapalumab, Cyclophosphamide, Fludarabine and Axicabtagene ciloleucel in Non-Hodgkin lymphoma, Diffuse large B-cell lymphoma, Primary mediastinal and Follicular lymphoma, run by Marcela V. Maus, M.D.,Ph.D., now recruiting.
Overview
Emapalumab Prevention of CAR-T Cell Associated Toxicities is a phase 2 interventional study registered as NCT06550141 by Marcela V. Maus, M.D.,Ph.D., with 28 participants planned, started 2024-09-18 and due to reach its primary completion in 2026-08-01. Interventions recorded: Emapalumab, Cyclophosphamide, Fludarabine Phosphate, Axicabtagene Ciloleucel. Conditions recorded: Large B-cell Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, Primary Mediastinal Large B-cell Lymphoma, High-grade B-cell Lymphoma, Follicular Lymphoma.
Linked to the drug Emapalumab because the registry names it among its interventions and Non-Hodgkin lymphoma, Diffuse large B-cell lymphoma, Primary mediastinal and Follicular lymphoma among its conditions. Registry record only: no result has been read by an editor.
Similar pages
not linked directly; found by shared links- TrialDose Escalation and Dose Expansion Study of MDX2003 in Patients With Different Types of Lymphoma
Shares Follicular lymphoma, Non-Hodgkin lymphoma (all types), Diffuse large B-cell lymphoma and the tag pipeline.
- TrialEmapalumab Prophylaxis of Bispecific T-Cell Engagers (BiTEs) Associated CRS and ICANS
Shares Emapalumab and the tag pipeline.
- TrialBiomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors
Shares Fludarabine, Cyclophosphamide and the tag pipeline.
- TrialDual-Target GD2/B7-H3 CAR-NK Cells for Pediatric Relapsed or Refractory Neuroblastoma
Shares Fludarabine, Cyclophosphamide and the tag pipeline.
- TrialConsolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Shares Fludarabine, Cyclophosphamide, Diffuse large B-cell lymphoma and the tag pipeline.
- TrialDual-target CLDN18.2/HER2 CAR-NK Cells for Advanced Gastric/GEJ Cancer
Shares Fludarabine, Cyclophosphamide and the tag pipeline.
- TrialGene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)
Shares Follicular lymphoma, Non-Hodgkin lymphoma (all types), Diffuse large B-cell lymphoma and the tag pipeline.
- TrialPhase 1/2 Study of CD19 Chimeric Antigen Receptor T-cell (CD19 CAR-T; PL001) for Relapsed or Refractory B-cell Lymphoma
Shares Follicular lymphoma, Diffuse large B-cell lymphoma and the tag pipeline.