Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Ar

Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial is a phase 2, interventional study registered as NCT07279077 by Sixth Affiliated Hospital, Sun Yat-sen University, with a registry enrolment figure of 38 participants, started 2025-11-26 and due to reach its primary completion in 2030-11-25. Interventions recorded: Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor. Conditions listed: Colon Cancer; Neoadjuvant Therapies; Immune Checkpoint Therapy; Radiation Therapy. Primary outcome: Pathological Complete Response(pCR) Rate. Colorectal eligibility wording from the registry: "Histologically confirmed adenocarcinoma of the colon (without squamous or sarcomatoid components)". Sites: China. No results are recorded here; the registry entry is the source.