Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study

Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study is a phase 2, randomised interventional study registered as NCT06594692 by Sir Run Run Shaw Hospital, with a registry enrolment figure of 140 participants, started 2024-10 and due to reach its primary completion in 2025-09-30. Interventions recorded: Node-Sparing Short-Course Radiotherapy Combined with CAPOX and Sintilimab; CAPOX Chemotherapy. Conditions listed: Microsatellite Stable (MSS) Colon Cancer; Locally Advanced Colon Cancer. Primary outcome: pathological complete response rate. Colorectal eligibility wording from the registry: "Tumor confirmed by colonoscopy and enhanced abdominal CT to be ≥ 12 cm from the anal verge". Sites: China. No results are recorded here; the registry entry is the source.