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BCB-214 is an experimental CAR T cell therapy from BrainChild Bio, at a stage the company does not state for glioblastoma and diffuse midline glioma.
BCB-214 is a CAR T cell therapy (triple-targeting) from BrainChild Bio. A triple-targeting CAR T cell therapy against EGFR, B7-H3 and IL13Ralpha2, combined with the company's functional retention technologies and repeated intracerebroventricular dosing, designed to overcome tumour heterogeneity and the immunosuppressive tumour microenvironment. The company does not state its stage; it is aimed at glioblastoma and diffuse midline glioma. No clinical trial naming it is registered on ClinicalTrials.gov. The pipeline page gives no stage; no ClinicalTrials.gov study names BCB-214 (query.intr=BCB-214 returned 0 on 3 Nov 2026). It has not been shown to work in people.
A triple-targeting CAR T cell therapy against EGFR, B7-H3 and IL13Ralpha2, combined with the company's functional retention technologies and repeated intracerebroventricular dosing, designed to overcome tumour heterogeneity and the immunosuppressive tumour microenvironment. Connects to EGFR and B7-H3.
1.BCB-214 slips into a pocket on EGFR.
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Query for this drug: (TITLE:"BCB-214" OR ABSTRACT:"BCB-214") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about BCB-214, not a curated reading list.
Shares B7-H3 and the tag pipeline.
Shares EGFR and the tag pipeline.
Shares EGFR and the tag pipeline.
Shares EGFR and the tag pipeline.
Shares EGFR and the tag pipeline.
Shares EGFR and the tag pipeline.
Shares EGFR and the tag pipeline.
Shares EGFR and the tag pipeline.
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