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A tissue test for cancers whose starting point cannot be found that reads 92 genes to suggest which organ the cancer came from.
Hologic states that "CancerTYPE ID uses real-time RT-PCR to measure the expression of 92-genes in the patient's tumor" and "can differentiate between 50 different tumor types and subtypes", and that "It has not been cleared or approved by the U.S. Food and Drug Administration." In a multisite validation of 790 tumours its overall sensitivity was 87 per cent for tumour type and 82 per cent for subtype (Kerr 2012). Palmetto MolDX article A53101 gives Medicare billing instructions for it under CPT 81540; the article does not itself state coverage.
Real-time RT-PCR of 92 genes in the tumour is matched against a reference database of known tumour types to give a molecular diagnosis of where the cancer started.
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Query for this drug: (TITLE:"CancerTYPE ID" OR ABSTRACT:"CancerTYPE ID" OR TITLE:"Cancer TYPE ID" OR ABSTRACT:"Cancer TYPE ID" OR TITLE:"92-gene molecular cancer classifier" OR ABSTRACT:"92-gene molecular cancer classifier") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CancerTYPE ID, not a curated reading list.
Shares Gene-expression prognostic assays, RNA sequencing & expression profiling and the tags test, rna.
Shares Gene-expression prognostic assays, RNA sequencing & expression profiling and the tags test, rna.
Shares Gene-expression prognostic assays, RNA sequencing & expression profiling and the tags test, rna.
Shares Gene-expression prognostic assays, RNA sequencing & expression profiling and the tags test, rna.
Shares Gene-expression prognostic assays and the tags test, rna.
Shares Gene-expression prognostic assays and the tags test, rna.
Shares Gene-expression prognostic assays and the tags test, rna.
Shares RNA sequencing & expression profiling and the tags test, rna.
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