Loading
A tissue test for ductal carcinoma in situ, the earliest non-invasive stage of breast cancer, that estimates the chance of it coming back in the same breast to help decide whether radiotherapy is needed.
Exact Sciences describes the test as "A tumor-tissue early-stage DCIS breast cancer test that shows how likely breast cancer will return and possible radiation benefit". In the ECOG E5194 cohort of 327 women treated by excision without radiotherapy, the ten-year risks of an ipsilateral breast event were 10.6, 26.7 and 25.9 per cent for low, intermediate and high scores (Solin 2013). Medicare's Palmetto MolDX policy L36912 covers it only when DCIS is found on biopsy with no invasive disease, the patient is a candidate for breast-conserving surgery, the result will be used to choose between surgery alone and surgery with radiotherapy, and no mastectomy is received or planned.
Reverse-transcription PCR on the Oncotype DX platform measures seven cancer-related genes and five reference genes in the removed DCIS tissue and reports a score for the ten-year risk of a local recurrence.
| Country | Reimbursement | List price | Assistance |
|---|---|---|---|
| United States | Medicare (Palmetto MolDX, L36912) covers it for ductal carcinoma in situ without invasive disease when the result will decide between breast-conserving surgery alone and surgery with radiotherapy | not disclosed | - |
List prices are manufacturer or Medicare figures where publicly disclosed; net prices after rebates are usually lower. Reimbursement changes; check the payer.
Country and place are remembered in this browser only. A postcode is sent to OpenStreetMap's Nominatim service to find coordinates when you press the button; nothing else leaves your device.
Query for this drug: (TITLE:"Oncotype DX Breast DCIS Score" OR ABSTRACT:"Oncotype DX Breast DCIS Score" OR TITLE:"Oncotype DX DCIS Score" OR ABSTRACT:"Oncotype DX DCIS Score" OR TITLE:"Oncotype DX DCIS" OR ABSTRACT:"Oncotype DX DCIS" OR TITLE:"DCIS Score" OR ABSTRACT:"DCIS Score") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Oncotype DX Breast DCIS Score, not a curated reading list.
Shares Exact Sciences (Abbott), Gene-expression prognostic assays, Oncotype DX, RNA sequencing & expression profiling and the tags test, rna.
Shares Gene-expression prognostic assays, RNA sequencing & expression profiling and the tags test, rna.
Shares Gene-expression prognostic assays, RNA sequencing & expression profiling and the tags test, rna.
Shares Gene-expression prognostic assays, RNA sequencing & expression profiling and the tags test, rna.
Shares Gene-expression prognostic assays and the tags test, rna.
Shares Gene-expression prognostic assays and the tags test, rna.
Shares Gene-expression prognostic assays and the tags test, rna.
Shares RNA sequencing & expression profiling and the tags test, rna.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/