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IDP-001 is an experimental bispecific antibody-drug conjugate from InduPro Therapeutics, in phase 1 trials for non-small cell lung cancer, head and neck squamous cell carcinoma and cutaneous squamous cell carcinoma and other cancers.
IDP-001 is a bispecific antibody-drug conjugate from InduPro Therapeutics. A proximity-based bispecific antibody-drug conjugate designed to target both EGFR and a novel tumour-associated antigen whose name the company has blinded (TAPA-E1). The company says dual targeting enhances tumour selectivity, target internalisation and efficacy. Its furthest stage is phase 1, for non-small cell lung cancer (squamous and non-squamous), head and neck squamous cell carcinoma, cutaneous squamous cell carcinoma and cervical squamous cell carcinoma. ClinicalTrials.gov registers it in one study linked below. First patient dosed in phase 1, announced 12 August 2026; NCT07602842 recruiting (registry lists phase 1/2). Whether it works in people has not been established unless a trial below reports it.
A proximity-based bispecific antibody-drug conjugate designed to target both EGFR and a novel tumour-associated antigen whose name the company has blinded (TAPA-E1). The company says dual targeting enhances tumour selectivity, target internalisation and efficacy. Connects to EGFR.
1.IDP-001's antibody arm binds EGFR on the surface of the cancer cell.
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Query for this drug: (TITLE:"IDP-001" OR ABSTRACT:"IDP-001") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about IDP-001, not a curated reading list.
Shares InduPro Therapeutics, EGFR and the tag pipeline.
Shares Cutaneous squamous cell carcinoma, EGFR, Cervical cancer, Head and neck squamous cell carcinoma and the tag pipeline.
Shares Oesophageal squamous cell carcinoma, Cervical cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Oesophageal squamous cell carcinoma, Cervical cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares InduPro Therapeutics and the tag pipeline.
Shares InduPro Therapeutics and the tag pipeline.
Shares EGFR, Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Cervical cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
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