SC-102 is an experimental peptide-drug conjugate from ConjuStar Biologics, in phase 1 trials for ephA2-expressing advanced or metastatic solid tumours.
SC-102 is a peptide-drug conjugate from ConjuStar Biologics. A peptide-drug conjugate made of an EphA2-targeting peptide, a tubulin-inhibitor payload and a protease-cleavable linker. Its furthest stage is phase 1, for ephA2-expressing advanced or metastatic solid tumours. ClinicalTrials.gov registers it in one study linked below. US FDA IND clearance announced 4 June 2025 (company news); phase 1 recruiting (NCT06710158). Whether it works in people has not been established unless a trial below reports it.
A peptide-drug conjugate made of an EphA2-targeting peptide, a tubulin-inhibitor payload and a protease-cleavable linker. Connects to EphA2 receptor.
1.SC-102's antibody arm binds EphA2 receptor on the surface of the cancer cell.
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Query for this drug: (TITLE:"SC-102" OR ABSTRACT:"SC-102") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about SC-102, not a curated reading list.
Shares ConjuStar Biologics, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares ConjuStar Biologics and the tag pipeline.
Shares ConjuStar Biologics, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
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