An Epstein-Barr virus vaccine to prevent nasopharyngeal cancer and lymphomas
EBV infects almost everyone and causes nasopharyngeal cancer, some lymphomas and some stomach cancers. A vaccine given before infection could remove those cancers.
Moderna's mRNA-1189 and NIH gp350 nanoparticle vaccines are in early trials. Propose accelerated development with infection prevention and infectious mononucleosis as first endpoints, then deployment in high-incidence nasopharyngeal cancer regions.
- Prevention we already have is not deployed · Around four in ten cancers are preventable with tools we already own: vaccines, tobacco control, weight, alcohol, sun and infection control.
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