EAU-ASCO collaborative guideline on penile cancer, 2023 update
The joint European and American guideline for penile cancer, from HPV testing and organ-sparing surgery to sentinel node biopsy, lymph node surgery and chemotherapy for node-positive disease.
Overview
Collaborative guideline from the European Association of Urology and the American Society of Clinical Oncology covering diagnosis, HPV and p16 testing, penile-preserving treatment (topical therapy, laser, glansectomy, partial penectomy), management of the groin nodes with dynamic sentinel node biopsy or inguinal lymphadenectomy, neoadjuvant and adjuvant chemotherapy for node-positive disease, radiotherapy, follow-up and sexual and psychological support.
It grades the evidence, most of which is retrospective, and recommends referral to centralised centres and enrolment in trials such as InPACT.
The standard-of-care entries on the penile cancer pages, from keeping as much of the penis as is safe to staging the groins with a sentinel node procedure, follow this guideline.
- Almost all recommendations rest on retrospective series; randomised evidence in penile cancer is limited to the InPACT trial.
- Access to dynamic sentinel node biopsy is limited to specialised centres.
Similar pages
not linked directly; found by shared links- Key paperWHO classification of tumours of the urinary system and male genital organs, 2022: renal, penile and testicular tumours
Shares European Urology, Localised penile cancer (organ-confined, node-negative).
- TermHPV status (HPV-positive / HPV-negative)
Shares Localised penile cancer (organ-confined, node-negative), Node-positive and metastatic penile cancer.
- TermLymphadenectomy (lymph node dissection)
Shares Localised penile cancer (organ-confined, node-negative), Node-positive and metastatic penile cancer.
- TermHPV-positive (p16) head and neck cancer
Shares Localised penile cancer (organ-confined, node-negative), Node-positive and metastatic penile cancer.
- CancerPenile cancer
Shares Localised penile cancer (organ-confined, node-negative), Node-positive and metastatic penile cancer.