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The development of a gene-activity signature for skin melanoma that separated patients with a low and high chance of the cancer coming back.
A 28-gene signature (with control genes, the basis of the 31-gene test) classified primary melanomas; disease-free survival in the validation set was 97 per cent for class 1 and 31 per cent for class 2.
Gene activity in the primary melanoma adds risk information to stage.
Shares DecisionDx-Melanoma, Gene-expression prognostic assays, Melanoma.
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