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CD1c marks one of the two main dendritic cell types. Unlike most antigen presentation, CD1 molecules show fats rather than protein fragments to T cells.
CD1c is an MHC-like molecule that presents lipid rather than peptide antigens, and it marks conventional type 2 dendritic cells, the commoner of the two conventional subsets in blood. Separating dendritic cells into CD1c and CD141 subsets matters because they do different jobs, and only some of them cross-present tumour antigen to cytotoxic T cells.
In plain words · CD1c marks one of the two main dendritic cell types. Unlike most antigen presentation, CD1 molecules show fats rather than protein fragments to T cells.
CD1c marks one of the two main dendritic cell types. Unlike most antigen presentation, CD1 molecules show fats rather than protein fragments to T cells.
MHC-like molecule presenting lipid antigens; marks the cDC2 dendritic subset.
No product in this corpus aims at CD1c yet. Because it sits on the outside of the cell, it can be reached from the bloodstream: antibodies flag the cell, ADCs deliver a toxin, radioligands deliver radiation, and CAR-T or bispecifics bring a T cell.
MHC-like molecule presenting lipid antigens; marks the cDC2 dendritic subset.
Query for this target: (TITLE:"CD1c" OR ABSTRACT:"CD1c" OR TITLE:"CD1C" OR ABSTRACT:"CD1C" OR TITLE:"BDCA-1" OR ABSTRACT:"BDCA-1") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CD1c, not a curated reading list.
Shares CD11c, Antigen presentation & immune editing and the tag immune-marker.
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