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technologiesTechnologyEstablished

Carbon-ion therapy

Heavier charged particles that kill even radiation-resistant tumours, available at only a handful of centres worldwide.

Higher biological effectiveness than protons for hypoxic and slow-growing tumours (sarcoma, chordoma, adenoid cystic, pancreatic). About 15 centres worldwide (Japan, Germany, Italy, China, Austria); first US centre under construction at Mayo Clinic Jacksonville.

Schematic · not to scale
Carbon-ion beam (dense ionisation) · Bragg peak · No exit dose

How it works

Carbon nuclei deposit dense ionisation tracks causing clustered DNA damage with a sharp Bragg peak.

Strengths
  • Effective in radioresistant tumours
Limitations
  • Very few facilities
  • Cost

Latest papers

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Literature trend140 papers in the last 12 months+17% vs prior 12How this is computed
Latest papers · live from Europe PMC
Open in Europe PMC

Query for this technology: (TITLE:"carbon ion radiotherapy" OR ABSTRACT:"carbon ion radiotherapy" OR TITLE:"carbon-ion radiotherapy" OR ABSTRACT:"carbon-ion radiotherapy" OR TITLE:"heavy ion therapy" OR ABSTRACT:"heavy ion therapy"). Results are unfiltered search hits about Carbon-ion therapy, not a curated reading list.

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