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Phenom-2 and Recursion OS

A model trained on billions of cell microscopy images to read what a drug or gene knockout does to a cell.

Phenom-2 (2024, 1.9B parameters, 8B images) is Recursion's phenomics foundation model; with Boltz-2 and the Recursion OS it drives the company's oncology pipeline (e.g. REC-617 CDK7 inhibitor).

Generic schematic · not to scale · placeholder for the drug discovery front
Guide RNA library · Knockout → dependency

How it works

Phenom-2 is a masked autoencoder ViT over Cell Painting images.

Strengths
  • Scale of proprietary phenomics
Limitations
  • Clinical translation still to prove
Since
2024

Latest papers

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Latest papers · live from Europe PMC
Open in Europe PMC

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