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Methylation arrays measure, at hundreds of thousands of CpG sites, the fraction of DNA copies carrying a methyl mark; that fraction, between 0 and 1, is the beta value.
The Illumina Infinium methylation assay uses BeadChip technology for genome-wide profiling of human DNA methylation, quantifying methylation at many loci (Wikipedia); the 450k array covers about 450,000 CpG sites and the EPIC array about 850,000. Each site's beta value is the methylated signal over total signal. DNA methylation in promoters typically represses transcription and is a stable record of cell identity, which is why methylation classifiers work for brain tumours and why methylation adds tissue-of-origin information to expression.
Showing the technology this term belongs to: DNA methylation profiling.
Shares Tissue-of-origin signal in tumour data, Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Tissue-of-origin signal in tumour data, Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Tissue-of-origin signal in tumour data, Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Tissue-of-origin signal in tumour data, Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.