LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
A phase 2/3 trial of Prednisone, Vinblastine, Mercaptopurine, Methotrexate, Cytarabine, Cladribine and Human normal immunoglobulin in Langerhans cell histiocytosis, run by North American Consortium for Histiocytosis, active and no longer recruiting.
Overview
LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis is a phase 2/3 interventional study registered as NCT02205762 by North American Consortium for Histiocytosis, with 1400 participants planned, started 2016-11-02 and due to reach its primary completion in 2026-07. Interventions recorded: Prednisone, Vinblastine, mercaptopurine, INDOMETHACIN, Methotrexate, Cytosine Arabinoside, 2-chlorodeoxyadenosine, hematopoietic stem cell transplantation (RIC-HSCT), Intravenous immunoglobulin. Conditions recorded: Langerhans Cell Histiocytosis.
Linked to the drug Human normal immunoglobulin because the registry names it among its interventions and Langerhans cell histiocytosis among its conditions. Registry record only: no result has been read by an editor.
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