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CompassHER2-pCR tests whether people whose cancer clears with a shorter course of pre-surgery treatment can receive less chemotherapy afterward. Further treatment depends on what is found at surgery.
CompassHER2-pCR tests whether people whose cancer clears with a shorter course of pre-surgery treatment can receive less chemotherapy afterward. Further treatment depends on what is found at surgery.
Interventional study registered as NCT04266249, sponsored by ECOG-ACRIN Cancer Research Group. Registry phase: 2. Registry enrollment is 2,175 participants (actual). Registry status checked October 10, 2026: active not recruiting. UCSF lists this study as closed to local enrollment; local availability and overall registry status are separate. See the registry for full eligibility and current sites.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-10. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Trastuzumab emtansine, UCSF Helen Diller Family Comprehensive Cancer Center, Trastuzumab, Paclitaxel / nab-paclitaxel and the tags ucsf-breast-coverage, interventional.
Shares Trastuzumab emtansine, Pertuzumab, UCSF Helen Diller Family Comprehensive Cancer Center, Trastuzumab and the tags ucsf-breast-coverage, interventional.
Shares Trastuzumab emtansine, UCSF Helen Diller Family Comprehensive Cancer Center, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Paclitaxel / nab-paclitaxel, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares Pertuzumab, UCSF Helen Diller Family Comprehensive Cancer Center, Trastuzumab, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Paclitaxel / nab-paclitaxel, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Paclitaxel / nab-paclitaxel, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Paclitaxel / nab-paclitaxel, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
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