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Trials recruiting now, the landmark trials, the trials held by this cancer's subtypes, the key papers and what they mean, the latest literature, and the milestones year by year.
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1 trials on record are attached to one of the types below rather than to Cervical cancer itself. They are grouped by the type that holds them, so someone still working out which type they have can see the whole field from here.
These are the latest rates from Ethiopia's only population-based registry, and IARC applies the registry's rates to the whole country; they show breast and cervical cancer dominating in women and a relatively high rate of colorectal cancer.
HPV self-testing can start and keep running in a region under active war, a simpler route than clinic-based smear tests where services and people have been displaced.
Many people diagnosed with cancer in South Africa are living with HIV, which affects their treatment, but registry records often do not say so; the authors call on clinicians and pathologists to record HIV status at diagnosis.
A two-dose school programme in a country with high HIV prevalence produced reductions in infection similar to three-dose programmes in high-income countries, including in girls living with HIV, who are at higher risk of cervical cancer.
Cervical screening reached far fewer women than the 2016 to 2025 national plan aimed for, and the 2026 to 2035 plan moves to HPV testing, including self-sampling, and asks for insurance to pay for screening.
Shortening the time from diagnosis to first treatment matters most for cancers that can still be cured, which is the case the Philippines' 2019 cancer law makes for patient navigation and referral pathways.
Bangladesh can follow each screened woman from enrolment to treatment electronically, which the authors say only a few countries report doing, but most eligible women have not been screened and most who test positive do not reach the next test.
Cancers driven by HPV other than cervical cancer are rising quickly in South Africa, most among Black South Africans, which the authors link to high HPV and HIV co-infection; HIV prevention and HPV vaccination are the levers.
Query for this cancer: (TITLE:"Cervical cancer" OR ABSTRACT:"Cervical cancer" OR TITLE:"CESC" OR ABSTRACT:"CESC" OR TITLE:"TCGA-CESC" OR ABSTRACT:"TCGA-CESC" OR TITLE:"cervical squamous cell carcinoma and endocervical adenocarcinoma TCGA CESC cohort" OR ABSTRACT:"cervical squamous cell carcinoma and endocervical adenocarcinoma TCGA CESC cohort") AND (treatment OR therapy OR trial OR survival OR diagnosis). Results are unfiltered search hits about Cervical cancer, not a curated reading list.
Cytology screening cuts cervical cancer mortality by ~70% where implemented.
HPV18 follows in 1984; Nobel Prize 2008.
Five randomised trials show 30-50% mortality reduction; chemoradiation becomes standard for locally advanced disease.
Practice reverses to open surgery within months.
Swedish registry study shows ~88% cancer reduction in women vaccinated before 17.
Four practice-changing phase 3 results presented at ESMO 2023.