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companiesCompany
GIMEMA
aka Gruppo Italiano Malattie EMatologiche dell'Adulto, Italian Group for Adult Hematologic Diseases
Italy's adult haematology trials group, famous for making acute promyelocytic leukaemia curable without chemotherapy and for chemotherapy-free Philadelphia-positive ALL.
Overview
Founded in 1982, GIMEMA coordinates more than 100 Italian haematology centres from Rome. With the German AMLSG it ran APL0406, which showed all-trans retinoic acid plus arsenic trioxide beats chemotherapy in low-to-intermediate risk acute promyelocytic leukaemia, and its LAL2116 D-ALBA trial showed dasatinib followed by blinatumomab can induce deep molecular responses in Ph-positive ALL without cytotoxic chemotherapy. GIMEMA also runs CML, CLL, myeloma and MDS trials and a central laboratory network for molecular monitoring. Its quality-of-life working party pioneered patient-reported outcomes in haematology trials.
Headquarters
Rome, IT
Scorecard
All companies#68of 1243 companies, score 59
- approved products +12
- targets +6
- modalities +4
- regions +7
- registry trials +30
2 approved, 0 in phase 3, 0 earlier, 3 targets, 660 registry studies. Formula on the scorecards page.
Website
Founded
1982
Antonio Cuneo
President of the Scientific Committee
HaematologyChronic lymphocytic leukaemiaCytogenetics
Ferrara haematologist and CLL expert who chairs GIMEMA's Scientific Committee.
Marco Vignetti
President
HaematologyAcute leukaemiaClinical trials
Haematologist who presides over GIMEMA, Italy's adult haematological malignancies cooperative group, and co-authored its chemotherapy-free Ph+ ALL trial.
Notes
top- APL0406 (ATRA-arsenic in APL)
- D-ALBA (chemo-free Ph+ ALL)
- CML and CLL trials
- Central molecular monitoring laboratories
Similar pages
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Shares HOVON, Chronic lymphocytic leukaemia and the tag cooperative-group.
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- CompanyInternational Extranodal Lymphoma Study Group
Shares HOVON and the tag cooperative-group.
- CompanyALFA (Acute Leukemia French Association)
Shares Acute myeloid leukaemia and the tag cooperative-group.
- CompanyFILO (French Innovative Leukemia Organisation)
Shares Acute myeloid leukaemia and the tag cooperative-group.
- CompanyEuropean Myeloma Network
Shares Multiple myeloma and the tag cooperative-group.
cancers
4technologies
3drugs
2ApprovedBispecific T-cell engager (CD19×CD3)
Blinatumomab · Blincyto
ApprovedSmall-molecule kinase inhibitor (BCR-ABL, KIT, PDGFRA)
Imatinib · Gleevec