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Glycopyrronium dries up secretions. In the last days of life it is one of the medicines that can be tried for noisy breathing from secretions when this distresses the dying person.
The US injection label covers reduction of salivary, tracheobronchial and pharyngeal secretions in anaesthesia, intraoperative use against vagal reflex arrhythmias, protection against peripheral muscarinic effects when neuromuscular block is reversed, and peptic ulcer. NICE NG31 recommends considering a trial of medicine for noisy respiratory secretions if they cause the dying person distress, using one of atropine, glycopyrronium bromide, hyoscine butylbromide or hyoscine hydrobromide, monitoring at least every 12 hours (off-label in December 2015). The Robinul NDA was approved on 6 February 1975.
An anticholinergic that blocks muscarinic receptors, reducing saliva and airway secretions.
1.Glycopyrronium bromide slips into a pocket on its target.
| Region | Year | Indication |
|---|---|---|
| US | 1975 | Reduction of secretions and vagal reflexes in anaesthesia; reversal of neuromuscular block; peptic ulcer · Year is the Robinul NDA 017558 approval (Drugs@FDA) |
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Query for this drug: (TITLE:"Glycopyrronium bromide" OR ABSTRACT:"Glycopyrronium bromide" OR TITLE:"Robinul" OR ABSTRACT:"Robinul" OR TITLE:"glycopyrrolate" OR ABSTRACT:"glycopyrrolate") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Glycopyrronium bromide, not a curated reading list.
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Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
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