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Ciprofloxacin is an antibiotic. In the UK it is the fluoroquinolone licensed to prevent infection in adults whose white cell count is expected to fall very low after chemotherapy.
The Cipro label covers skin, bone and joint, intra-abdominal, urinary, respiratory and other infections, with boxed warnings about tendon, nerve and central nervous system effects. NICE CG151 offers adults with acute leukaemias, stem cell transplants or solid tumours in whom significant neutropenia is expected prophylaxis with a fluoroquinolone during the expected period of neutropenia only, and notes that "In September 2024, only ciprofloxacin was licensed for prophylaxis of infections in neutropenic patients", referring to MHRA January 2024 advice on fluoroquinolone restrictions. The Cipro NDA was approved on 22 October 1987.
A fluoroquinolone that inhibits bacterial DNA gyrase and topoisomerase IV.
1.Ciprofloxacin slips into a pocket on its target.
| Region | Year | Indication |
|---|---|---|
| US | 1987 | Skin, bone and joint, intra-abdominal, urinary, respiratory and other bacterial infections listed on the label · Year is the Cipro NDA 019537 approval (Drugs@FDA) |
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Query for this drug: (TITLE:"Ciprofloxacin" OR ABSTRACT:"Ciprofloxacin" OR TITLE:"Cipro" OR ABSTRACT:"Cipro" OR TITLE:"Ciproxin" OR ABSTRACT:"Ciproxin") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Ciprofloxacin, not a curated reading list.
Shares Febrile neutropenia and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares Neutropenia and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
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