STX-005 is an experimental circular mRNA circuit for in vivo CAR-T from Strand Therapeutics, in preclinical development for haematological malignancies.
STX-005 is a circular mRNA circuit for in vivo CAR-T (systemic) from Strand Therapeutics. A systemically delivered circular mRNA circuit designed to generate CAR-T cells inside the body. Its furthest stage is preclinical development, for haematological malignancies. No clinical trial naming it is registered on ClinicalTrials.gov. No registry entry; the company's site links an April 2026 press release on preclinical in vivo CAR-T data at ASGCT 2026 (BusinessWire blocked the fetch, so only the headline/URL was seen). It has not been shown to work in people.
A systemically delivered circular mRNA circuit designed to generate CAR-T cells inside the body.
1.STX-005 slips into a pocket on its target.
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Query for this drug: (TITLE:"STX-005" OR ABSTRACT:"STX-005") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about STX-005, not a curated reading list.
Shares Strand Therapeutics, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Strand Therapeutics, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Strand Therapeutics, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Strand Therapeutics, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
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