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A urine test that reads five RNA markers to check for bladder cancer coming back, and in a Danish trial halved the number of camera examinations of the bladder.
Cepheid describes "a non-invasive biomarker test for monitoring NMIBC patients for recurrence in conjunction with other clinical measures" built on "the five strongest bladder cancer indicator mRNAs", with a CE-IVD package insert. In the randomised DaBlaCa-15 trial in high-grade non-muscle-invasive bladder cancer, 1,029 cystoscopies were performed in the control arm and 445 in the arm guided by the test, the risk difference for high-grade recurrence was 0.08 per cent (95% CI minus 7.2 to 7.4), and two pTa high-grade recurrences were missed (Dreyer 2025). A longitudinal validation reported 87 per cent sensitivity for high-grade cancer and a negative predictive value of 99 per cent (Cowan 2021).
A cartridge test measures five mRNA markers in voided urine to flag likely recurrence of non-muscle-invasive bladder cancer.
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A urine RNA test cut camera examinations by more than half in this trial, with two missed recurrences.
A negative urine result makes a high-grade recurrence unlikely.
Query for this drug: (TITLE:"Xpert Bladder Cancer Monitor" OR ABSTRACT:"Xpert Bladder Cancer Monitor" OR TITLE:"Xpert BC Monitor" OR ABSTRACT:"Xpert BC Monitor" OR TITLE:"Cepheid Xpert Bladder" OR ABSTRACT:"Cepheid Xpert Bladder") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Xpert Bladder Cancer Monitor, not a curated reading list.
Shares Liquid RNA biopsy (cell-free, vesicle and platelet RNA) and the tags test, rna.
Shares Liquid RNA biopsy (cell-free, vesicle and platelet RNA) and the tags test, rna.
Shares Liquid RNA biopsy (cell-free, vesicle and platelet RNA) and the tags test, rna.
Shares Liquid RNA biopsy (cell-free, vesicle and platelet RNA) and the tags test, rna.
Shares Liquid RNA biopsy (cell-free, vesicle and platelet RNA) and the tags test, rna.
Shares Bladder & urothelial cancer and the tags test, rna.
Shares the tags test, rna.
Shares the tags test, rna.
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