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Surgeons often cannot see where a tumour ends. Fluorescent dyes and AI-read imaging in the operating theatre can show them, cutting repeat operations. Make this routine everywhere.
Positive margins lead to re-operation or recurrence in breast, head and neck, prostate and gastrointestinal surgery. Tumour-targeted fluorescent agents (pegulicianine approved for breast lumpectomy, PSMA- and folate-targeted agents), intraoperative mass spectrometry and rapid AI histology can assess margins during surgery. The proposal is a programme to standardise and validate these tools across common operations, integrate them into low-cost surgical imaging platforms suitable for district hospitals, and make margin status with intraoperative assessment a quality indicator.
Shares Global cancer surgery: delivering safe, affordable, and timely cancer surgery, Intraoperative margin assessment in breast-conserving surgery, Optical & fluorescence imaging, Fluorescence-guided surgery.
Shares Intraoperative margin assessment in breast-conserving surgery, Optical & fluorescence imaging, Fluorescence-guided surgery, Precision roadmap: margins measured in millimetres → tests that find a target → doses fitted to the person → precision that changes outcomes.
Shares Optical & fluorescence imaging, Digital pathology & AI, HR-positive / HER2-negative breast cancer.
Shares Global cancer surgery: delivering safe, affordable, and timely cancer surgery, Surgery and radiotherapy cure most, get least, HR-positive / HER2-negative breast cancer, Prostate cancer.
Shares Intraoperative margin assessment in breast-conserving surgery, Optical & fluorescence imaging, Fluorescence-guided surgery, HR-positive / HER2-negative breast cancer.
Shares Global cancer surgery: delivering safe, affordable, and timely cancer surgery, Digital pathology & AI, Surgery and radiotherapy cure most, get least, Prostate cancer.
Shares Global cancer surgery: delivering safe, affordable, and timely cancer surgery, Fluorescence-guided surgery, Surgery and radiotherapy cure most, get least.
Shares Intraoperative margin assessment in breast-conserving surgery, Precision roadmap: margins measured in millimetres → tests that find a target → doses fitted to the person → precision that changes outcomes.
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