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Stomach cancer is staged by how deep it has grown through the layers of the stomach wall and how many nearby lymph nodes contain it, from stage I to stage IV, where it has spread to distant organs.
AJCC chapter 17 covers the stomach and is an 8th edition chapter in the AJCC 2026 table. In the NCI's summary, stage IA cancer is in the mucosa and may reach the submucosa; later stages combine depth (submucosa, muscle layer, subserosa, serosa, nearby organs) with the number of nearby lymph nodes involved (1 to 2, 3 to 6, 7 to 15, 16 or more); stage IV means spread to distant parts of the body such as the lungs, liver, distant nodes or the lining of the abdomen. The Siewert and Lauren classifications describe location and histology, not stage. The stage descriptions are those in the National Cancer Institute's PDQ summary, which follows the AJCC tables.
Squamous cancers sit in the upper and middle oesophagus, adenocarcinomas at the junction and in the stomach; the stomach wall also gives rise to GIST from its pacemaker cells.
Same organ: HER2-positive gastric cancer, Claudin 18.2-positive gastric cancer, PD-L1-high gastric cancer, Microsatellite-unstable (MSI-high) gastric cancer, Early gastric cancer, Oesophageal squamous cell carcinoma, Oesophageal and junctional adenocarcinoma, Oesophageal cancer, Gastrointestinal stromal tumour (GIST), KIT exon 11-mutant GIST, PDGFRA D842V-mutant GIST, Imatinib-resistant GIST
Showing the organ this term concerns: Gastric & gastro-oesophageal junction cancer.
Shares AJCC stage (TNM staging manual), Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC), TNM staging.
Shares AJCC stage (TNM staging manual), Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC), TNM staging.
Shares AJCC stage (TNM staging manual), Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC), TNM staging.
Shares AJCC stage (TNM staging manual), Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC), TNM staging.
Shares Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC), TNM staging.
Shares Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC), TNM staging.
Shares Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC), TNM staging.
Shares Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC), TNM staging.
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