EORTC 26951
EORTC 26951, the European twin of RTOG 9402, confirmed that PCV chemotherapy after radiotherapy greatly lengthens survival in 1p/19q co-deleted oligodendrogliomas.
Overview
EORTC 26951 randomised 368 patients with anaplastic oligodendroglioma or oligoastrocytoma to 59.4 Gy radiotherapy with or without six cycles of adjuvant PCV. With a median follow-up of nearly 12 years, overall survival improved with PCV (42.3 versus 30.6 months overall); in 1p/19q co-deleted tumours median survival was not reached with PCV versus 112 months with radiotherapy alone (van den Bent and colleagues, Journal of Clinical Oncology 2013).
Similar pages
not linked directly; found by shared links- TrialRTOG 9402
Shares Procarbazine, Lomustine (CCNU), Chemoradiation (chemoradiotherapy, CRT), Brain and spinal cord tumours (all types) and the tag radiation-wave4.
- TrialEORTC 22033-26033
Shares Brain and spinal cord tumours (all types), IMRT / IGRT (modern external beam), Glioma & glioblastoma and the tag radiation-wave4.
- TrialCAO/ARO/AIO-94 (German Rectal Cancer Study)
Shares Chemoradiation (chemoradiotherapy, CRT), IMRT / IGRT (modern external beam) and the tag radiation-wave4.
- TrialINT-0116 (Macdonald trial)
Shares Chemoradiation (chemoradiotherapy, CRT), IMRT / IGRT (modern external beam) and the tag radiation-wave4.
- TrialPRODIGE 23
Shares Chemoradiation (chemoradiotherapy, CRT), IMRT / IGRT (modern external beam) and the tag radiation-wave4.
- TrialDe-ESCALaTE HPV
Shares Chemoradiation (chemoradiotherapy, CRT), IMRT / IGRT (modern external beam) and the tag radiation-wave4.
- TrialRTOG 1016
Shares Chemoradiation (chemoradiotherapy, CRT), IMRT / IGRT (modern external beam) and the tag radiation-wave4.
- TrialRTOG 91-11
Shares Chemoradiation (chemoradiotherapy, CRT), IMRT / IGRT (modern external beam) and the tag radiation-wave4.