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Breast Cancer Trials
aka BCT, Australia and New Zealand Breast Cancer Trials Group, ANZBCTG
The Australian and New Zealand breast cancer trials group, a Breast International Group partner in SOFT/TEXT, APHINITY, OlympiA and POSITIVE.
Overview
Founded in 1978 as the ANZ Breast Cancer Trials Group and renamed Breast Cancer Trials, it is one of the longest-running academic breast cancer groups and a founding member of the Breast International Group. It co-led the IBCSG SOFT and TEXT trials of ovarian suppression, contributed to APHINITY, OlympiA and the POSITIVE pregnancy-interruption study, and runs its own trials such as EXPERT (omitting radiotherapy in low-genomic-risk luminal A disease) and DECRESCENDO. A large consumer advisory panel shapes protocol design. Trials are coordinated from Newcastle with sites across Australia and New Zealand.
Headquarters
Newcastle, NSW, AU
Scorecard
All companies#62of 1243 companies, score 61
- approved products +12
- targets +6
- modalities +4
- regions +7
- 24-month regulatory events +2
- registry trials +30
2 approved, 0 in phase 3, 0 earlier, 3 targets, 1,543 registry studies. Formula on the scorecards page.
Founded
1978
Research output
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-24.
Matched to Breast Cancer Trials, including child institutions. 10 works · 554 citations · 60% open access · 30% clinical trials · 0% reviews.
Oncology works per year
22022
02023
32024
42025
12026
Most works
- Sherene Loi5 works
- Prudence A. Francis5 works
- Meredith M. Regan3 works
- Nicholas Zdenkowski3 works
- Richard D. Gelber3 works
- Marco Angelo Colleoni3 works
- Frances M. Boyle3 works
- Sally E. Baron-Hay2 works
- Rina Hui2 works
- Andrew David Redfern2 works
Most cited
Prudence A. Francis
Head of Breast Medical Oncology, Peter MacCallum Cancer Centre
Premenopausal breast cancerOvarian function suppressionAdjuvant endocrine therapy
Led SOFT and TEXT, the trials that showed ovarian suppression plus exemestane helps young women with breast cancer.
Sunil Lakhani
Chair of the Board
Breast pathologyBreast cancerMolecular pathology
Brisbane breast pathologist who chairs the board of Breast Cancer Trials, the Australia and New Zealand breast cancer clinical trials group.
Sherene Loi
Professor and Head, Translational Breast Cancer Genomics and Therapeutics Laboratory; medical oncologist, Peter Mac
Breast cancerTumour-infiltrating lymphocytesImmunotherapy
Showed that immune cells inside breast tumours predict outcome, the basis for de-escalating chemotherapy in TNBC.
Notes
top- SOFT / TEXT (with IBCSG)
- OlympiA and APHINITY (with BIG)
- EXPERT (radiotherapy omission)
- POSITIVE (pregnancy after endocrine therapy)
Similar pages
not linked directly; found by shared links- CompanyGEICAM Spanish Breast Cancer Group
Shares Breast International Group (BIG), Endocrine therapy (SERMs, AIs, SERDs), HER2-positive breast cancer, Triple-negative breast cancer (TNBC) and the tag cooperative-group.
- CompanySOLTI Cancer Research Group
Shares Breast International Group (BIG), Trastuzumab, HER2-positive breast cancer, Triple-negative breast cancer (TNBC) and the tag cooperative-group.
- CompanyAustrian Breast & Colorectal Cancer Study Group
Shares Breast International Group (BIG), Endocrine therapy (SERMs, AIs, SERDs), HER2-positive breast cancer, HR-positive / HER2-negative breast cancer and the tag cooperative-group.
- CompanyDanish Breast Cancer Group
Shares HER2-positive breast cancer, Triple-negative breast cancer (TNBC), HR-positive / HER2-negative breast cancer and the tag cooperative-group.
- CompanyNSABP Foundation
Shares Endocrine therapy (SERMs, AIs, SERDs), Trastuzumab, HER2-positive breast cancer, HR-positive / HER2-negative breast cancer and the tag cooperative-group.
- CompanyAustralasian Gastro-Intestinal Trials Group
Shares Cancer Council Australia, Peter MacCallum Cancer Centre and the tag cooperative-group.
- CompanyTROG Cancer Research
Shares Cancer Council Australia, Peter MacCallum Cancer Centre and the tag cooperative-group.
- CompanyANZUP Cancer Trials Group
Shares Cancer Council Australia, Peter MacCallum Cancer Centre and the tag cooperative-group.
cancers
3fronts
1technologies
2drugs
2ApprovedSmall-molecule PARP inhibitor
Olaparib · Lynparza
ApprovedMonoclonal antibody (anti-HER2)
Trastuzumab · Herceptin (and biosimilars, Phesgo with pertuzumab)