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ECOG-ACRIN Cancer Research Group
aka ECOG-ACRIN, Eastern Cooperative Oncology Group, ECOG, American College of Radiology Imaging Network, ACRIN
US cooperative group that pairs a therapy group with an imaging group; its E1910 trial moved blinatumomab into frontline leukaemia treatment.
Overview
Merger (2012) of the Eastern Cooperative Oncology Group and the American College of Radiology Imaging Network. E1910 showed adding blinatumomab consolidation improves survival in MRD-negative B-ALL, leading to the 2024 label. Also runs TMIST (tomosynthesis vs digital mammography screening) and the ECOG performance status scale.
Headquarters
Philadelphia, PA, US
Scorecard
All companies#104of 1243 companies, score 50
- approved products +6
- targets +4
- modalities +4
- regions +6
- registry trials +30
1 approved, 0 in phase 3, 0 earlier, 2 targets, 2,294 registry studies. Formula on the scorecards page.
Website
Founded
2012
Research output
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-14.
Matched to ECOG-ACRIN Cancer Research Group, including child institutions. 15 works · 142 citations · 47% open access · 47% clinical trials · 0% reviews.
Oncology works per year
62022
42023
32024
02025
22026
Most works
- Lynne I. Wagner7 works
- Ilana F. Gareen5 works
- Fengmin Zhao4 works
- David Cella4 works
- Ju‐Whei Lee4 works
- Ruth C. Carlos4 works
- Robert J. Gray4 works
- Joseph A. Sparano4 works
- Carlos L. Arteaga3 works
- Kathy D. Miller3 works
Most cited
EstablishedOral cytotoxic regimen
CAPTEM (capecitabine plus temozolomide) is an all-oral chemotherapy pair that shrinks pancreatic neuroendocrine tumours in about a third of patients.
Mark R. Litzow
Professor of Medicine, Mayo Clinic; Chair, ECOG-ACRIN Leukemia Committee; Study Chair, E1910
Acute lymphoblastic leukaemiaImmunotherapyTransplant
Leukaemia specialist who led E1910, the trial that put blinatumomab into frontline treatment for adults in remission.
Mitchell D. Schnall
Group Co-Chair, ECOG-ACRIN Cancer Research Group; Chair of Radiology, University of Pennsylvania
ImagingBreast MRIImaging trials
Mitchell Schnall is the radiologist who brought imaging research into the ECOG-ACRIN cooperative group.
Peter J. O'Dwyer
Group Co-Chair, ECOG-ACRIN Cancer Research Group; Professor of Medicine, University of Pennsylvania
Gastrointestinal oncologyDrug developmentCooperative group trials
Peter O'Dwyer is a GI oncologist who co-leads ECOG-ACRIN, one of the NCI's national trial networks.
Shaji K. Kumar
Professor of Medicine; Chair, Myeloma, Amyloidosis and Dysproteinemia Group, Mayo Clinic
Multiple myelomaClinical trialsMRD
Myeloma trialist who led venetoclax and quadruplet studies and helped define MRD response criteria.
Notes
top- NCTN cooperative group
- E1910 blinatumomab
- TMIST screening trial
- Imaging biomarker trials
Similar pages
not linked directly; found by shared links- CompanySWOG Cancer Research Network
Shares A publicly held library of investigational drugs available for academic combination trials, Follow every trial participant for 30 years through registry linkage, A fixed share of trial-group funding for getting proven care to patients, ALCHEMIST (Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials) and the tag cooperative-group.
- CompanyAlliance for Clinical Trials in Oncology
Shares ALCHEMIST (Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials), Lung-MAP (SWOG S1400 and S1900), Older and multimorbid patients are excluded and undertreated, Trial modernisation roadmap: the randomised trial → platforms and adaptive designs → decentralised, pragmatic and always-on and the tag cooperative-group.
- CompanyNRG Oncology
Shares ALCHEMIST (Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials), Lung-MAP (SWOG S1400 and S1900), Trial modernisation roadmap: the randomised trial → platforms and adaptive designs → decentralised, pragmatic and always-on, Trials enrol too few, too slowly and the tag cooperative-group.
- CompanyCanadian Cancer Trials Group (CCTG)
Shares A publicly held library of investigational drugs available for academic combination trials, Trial modernisation roadmap: the randomised trial → platforms and adaptive designs → decentralised, pragmatic and always-on, Trials enrol too few, too slowly and the tag cooperative-group.
- CompanyChildren's Oncology Group (COG)
Shares Follow every trial participant for 30 years through registry linkage, University of Wisconsin Carbone Cancer Center, Blinatumomab, Trial modernisation roadmap: the randomised trial → platforms and adaptive designs → decentralised, pragmatic and always-on and the tag cooperative-group.
- CompanyGIMEMA
Shares Blinatumomab, Acute lymphoblastic leukaemia and the tag cooperative-group.
- CompanyEORTC
Shares A fixed share of trial-group funding for getting proven care to patients, Secrecy and intellectual property block collaboration and the tag cooperative-group.
- CompanyUNICANCER
Shares A publicly held library of investigational drugs available for academic combination trials, Trials enrol too few, too slowly and the tag cooperative-group.
cancers
3technologies
1drugs
2ApprovedBispecific T-cell engager (CD19×CD3)
Blinatumomab · Blincyto
EstablishedOral cytotoxic regimen
institutions
3trials
11roadmaps
2ideas
5A fixed share of trial-group funding for getting proven care to patientsA national platform trial that every ctDNA-positive patient can joinA publicly held library of investigational drugs available for academic combination trialsChemotherapy before the second operation for high-risk incidental gallbladder cancerFollow every trial participant for 30 years through registry linkage