Montefiore Einstein Comprehensive Cancer Center
The Bronx's NCI comprehensive cancer centre, where Joseph Sparano ran TAILORx, the trial that let most women with early HR-positive breast cancer skip chemotherapy.
The Albert Einstein Cancer Center has been NCI-designated since 1972 and, as Montefiore Einstein Comprehensive Cancer Center, now holds comprehensive status while serving one of the poorest urban counties in the United States. Joseph Sparano chaired TAILORx from here for ECOG-ACRIN, showing that a mid-range Oncotype DX recurrence score identifies women who do not need adjuvant chemotherapy. John Condeelis's intravital imaging revealed the TMEM 'doorways' through which breast cancer cells enter the bloodstream; Ulrich Steidl and Amit Verma lead work on MDS and leukaemia stem cells. Director Edward Chu is a GI oncologist and cancer pharmacologist.
- Breast cancer (TAILORx)
- Metastasis imaging
- MDS and leukaemia stem cells
- Bronx community oncology
Pages like this
not linked directly; found by shared links- PersonKathy S. Albain
Shares TAILORx, Oncotype DX, HR-positive / HER2-negative breast cancer.
- PairingGene-expression assay → chemotherapy omission
Shares TAILORx, Oncotype DX, HR-positive / HER2-negative breast cancer.
- InstitutionSylvester Comprehensive Cancer Center, University of Miami
Shares Myelodysplastic syndromes / neoplasms (MDS), Trials do not represent the people who get cancer, Acute myeloid leukaemia.
- IdeaA formal regulatory route for validating a biomarker on archived trial samples
Shares TAILORx, Oncotype DX.
- ProductPegulicianine
Shares Optical & fluorescence imaging, HR-positive / HER2-negative breast cancer.
- InstitutionChao Family Comprehensive Cancer Center, UC Irvine
Shares Optical & fluorescence imaging, Acute myeloid leukaemia.
- ProductMammaPrint (70-gene signature)
- CompanyExact Sciences (Abbott)
Shares Oncotype DX, HR-positive / HER2-negative breast cancer.