Loading
Propofol is an anaesthetic given into a vein for operations and deep sedation. Children with cancer may have it for lumbar punctures and other procedures, and in palliative care it is a last-step option for sedation, given under an anaesthetist.
The Diprivan label covers monitored anaesthesia care sedation, combined sedation and regional anaesthesia, induction and maintenance of general anaesthesia and sedation of ventilated patients in intensive care. The international guideline on needle procedures in children with cancer (Loeffen 2020) strongly recommends offering deep sedation or general anaesthesia to all children having a lumbar puncture; NICE CG112 requires a professional trained in delivering anaesthetic agents to be available whenever propofol, sevoflurane or opioids with ketamine are used for sedation in under-19s. In the EAPC 2024 palliative sedation framework propofol is step 3, "Administration under the supervision of an anaesthesiologist is advisable". The Diprivan NDA was approved on 2 October 1989.
A short-acting intravenous anaesthetic that enhances GABA-A receptor signalling.
1.Propofol slips into a pocket on its target.
| Region | Year | Indication |
|---|---|---|
| US | 1989 | Induction and maintenance of general anaesthesia; procedural and intensive care sedation · Year is the Diprivan NDA 019627 approval (Drugs@FDA) |
Country and place are remembered in this browser only. A postcode is sent to OpenStreetMap's Nominatim service to find coordinates when you press the button; nothing else leaves your device.
Query for this drug: (TITLE:"Propofol" OR ABSTRACT:"Propofol" OR TITLE:"Diprivan" OR ABSTRACT:"Diprivan") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Propofol, not a curated reading list.
Shares Midazolam and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares Levomepromazine and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares Levomepromazine and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/