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CCR6 marks the T cells that patrol mucosal surfaces such as the gut and airway, and it is the usual way of picking out the Th17 type of helper cell.
CCR6 binds CCL20 and directs cells to mucosal tissue, and it is the surface marker conventionally used to identify Th17-polarised helper T cells. In an immune panel it is read together with CXCR3 and CCR4 to assign helper T cells to their functional types, a division that matters when describing what sort of response a tumour or a treatment has provoked.
In plain words · CCR6 marks the T cells that patrol mucosal surfaces such as the gut and airway, and it is the usual way of picking out the Th17 type of helper cell.
CCR6 marks the T cells that patrol mucosal surfaces such as the gut and airway, and it is the usual way of picking out the Th17 type of helper cell.
Receptor for CCL20; marks Th17-polarised T cells and directs cells to mucosal tissue.
No product in this corpus aims at CCR6 yet. Because it sits on the outside of the cell, it can be reached from the bloodstream: antibodies flag the cell, ADCs deliver a toxin, radioligands deliver radiation, and CAR-T or bispecifics bring a T cell.
Receptor for CCL20; marks Th17-polarised T cells and directs cells to mucosal tissue.
Query for this target: (TITLE:"CCR6" OR ABSTRACT:"CCR6") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CCR6, not a curated reading list.
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