Loading
CD4 is the marker of helper T cells, the cells that direct an immune response rather than kill infected or cancerous cells themselves. A CD4 count is how the strength of that arm of the immune system is measured.
CD4 is a surface co-receptor that binds MHC class II and defines the helper T cell lineage. Helper T cells do not kill target cells directly; they license other cells to, which is why a CD4 count is the standard measure of that arm of the immune system in transplant, infection and after chemotherapy. CD4 is also present at lower levels on monocytes, macrophages and dendritic cells. In an immunophenotyping panel CD4 and CD8 are the pair that split the T cell compartment, and nearly every statement on this site about T cell infiltration or recovery rests on them. CD4 is separately known as the receptor HIV uses to enter cells.
In plain words · CD4 is the marker of helper T cells, the cells that direct an immune response rather than kill infected or cancerous cells themselves. A CD4 count is how the strength of that arm of the immune system is measured.
CD4 is the marker of helper T cells, the cells that direct an immune response rather than kill infected or cancerous cells themselves. A CD4 count is how the strength of that arm of the immune system is measured.
Co-receptor on helper T cells; binds MHC class II and marks the helper lineage.
No product in this corpus aims at CD4 yet. Because it sits on the outside of the cell, it can be reached from the bloodstream: antibodies flag the cell, ADCs deliver a toxin, radioligands deliver radiation, and CAR-T or bispecifics bring a T cell.
Co-receptor on helper T cells; binds MHC class II and marks the helper lineage.
Query for this target: (TITLE:"CD4" OR ABSTRACT:"CD4" OR TITLE:"CD4 molecule" OR ABSTRACT:"CD4 molecule" OR TITLE:"T4" OR ABSTRACT:"T4") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CD4, not a curated reading list.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/