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Biobanking and tissue procurement

Freezers full of consented tumour samples with matched clinical data, which every biomarker and drug programme depends on.

Academic biobanks (MD Anderson, Mayo, UK Biobank for germline, Karolinska, Hartwig for WGS), commercial procurement (Discovery Life Sciences, Indivumed, BioIVT, Precision for Medicine, iSpecimen marketplace), and living biobanks of organoids and PDX (Hubrecht Organoid Technology, Champions Oncology, HCMI) supply tissue, blood, and models for target validation and diagnostic development. Consent breadth, annotation depth, and pre-analytic standardisation determine value.

Generic schematic · not to scale · placeholder for the drug discovery front
Guide RNA library · Knockout → dependency

How it works

Consented collection at surgery or biopsy, controlled fixation or snap-freezing, LIMS tracking, and linked de-identified clinical follow-up.

Strengths
  • Enables retrospective biomarker validation
  • Living biobanks allow functional testing
Limitations
  • Consent and governance
  • Pre-analytic variability
  • Under-representation of many populations

Latest papers

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Query for this technology: (TITLE:"Biobanking and tissue procurement" OR ABSTRACT:"Biobanking and tissue procurement") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Biobanking and tissue procurement, not a curated reading list.

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